{"id":19531,"date":"2022-08-18T12:45:56","date_gmt":"2022-08-18T10:45:56","guid":{"rendered":"https:\/\/naturalpoland.pl\/artykuly\/prirodni-produkty\/jsou-glykosidy-steviolu-zdrave\/"},"modified":"2022-08-18T12:45:57","modified_gmt":"2022-08-18T10:45:57","slug":"jsou-glykosidy-steviolu-zdrave","status":"publish","type":"post","link":"https:\/\/naturalpoland.com\/cs\/artykuly\/prirodni-produkty\/jsou-glykosidy-steviolu-zdrave\/","title":{"rendered":"Jsou glykosidy steviolu zdrav\u00e9?"},"content":{"rendered":"\n

Glykosidy steviolu jsou chemick\u00e9 slou\u010deniny, kter\u00e9 se izoluj\u00ed z list\u016f Stevia rebaudiana<\/strong><\/em>, rostliny rostouc\u00ed v Ji\u017en\u00ed Americe a pou\u017e\u00edvan\u00e9 domorod\u00fdmi obyvateli po stovky let. Chemick\u00e1 struktura glykosid\u016f steviolu je stabiln\u00ed a b\u011bhem procesu extrakce a \u010di\u0161t\u011bn\u00ed se nem\u011bn\u00ed \u2013 lze tedy p\u0159edpokl\u00e1dat, \u017ee glykosidy steviolu jsou zcela p\u0159\u00edrodn\u00edm produktem. \u010cetn\u00e9 senzorick\u00e9 testy ukazuj\u00ed, \u017ee glykosidy steviolu jsou a\u017e 300kr\u00e1t slad\u0161\u00ed ne\u017e tradi\u010dn\u00ed sachar\u00f3za<\/strong>. Od 70. let se v Japonsku pou\u017e\u00edvaj\u00ed jako p\u0159\u00edsada do potravin. Ve Spojen\u00fdch st\u00e1tech byly ozna\u010deny FDA jako zcela bezpe\u010dn\u00e9 se symbolem GRAS (Generally Recognized As Saf<\/em>e). V roce 2011 je Evropsk\u00e1 unie schv\u00e1lila jako potravin\u00e1\u0159skou p\u0159\u00eddatnou l\u00e1tku, ozna\u010denou symbolem<\/strong> E-960<\/strong>. <\/p>\n\n

Evropsk\u00fd \u00fa\u0159ad pro bezpe\u010dnost potravin p\u0159ezkoumal bezpe\u010dnost st\u00e9vie a doporu\u010duje p\u0159ijateln\u00fd denn\u00ed p\u0159\u00edjem glykosid\u016f steviolu v d\u00e1vce 4 mg\/kg t\u011blesn\u00e9 hmotnosti<\/strong>. Studie toxicity, jejich\u017e \u00fa\u010delem je prozkoumat \u0161kodliv\u00e9 \u00fa\u010dinky testovan\u00e9 slou\u010deniny vypl\u00fdvaj\u00edc\u00ed z jej\u00edch vlastnost\u00ed, uk\u00e1zaly, \u017ee glykosidy nejsou teratogenn\u00ed (tj. nemaj\u00ed \u017e\u00e1dn\u00fd toxick\u00fd \u00fa\u010dinek na embryo nebo plod), mutagenn\u00ed ani karcinogenn\u00ed. Nevykazuj\u00ed rovn\u011b\u017e akutn\u00ed toxicitu (p\u0159i pod\u00e1v\u00e1n\u00ed ve vysok\u00fdch d\u00e1vk\u00e1ch) kr\u00e1tce po pod\u00e1n\u00ed nebo subakutn\u00ed toxicitu p\u0159i dlouhodob\u00e9m u\u017e\u00edv\u00e1n\u00ed. St\u00e9vie je bezpe\u010dn\u00e1 i pro t\u011bhotn\u00e9 a koj\u00edc\u00ed \u017eeny, pokud jej\u00ed konzumace nep\u0159ekro\u010d\u00ed maxim\u00e1ln\u00ed povolenou d\u00e1vku. <\/p>\n\n

Glykosidy steviolu<\/a> a cukrovka<\/h2>\n\n

Studie ADME (vst\u0159eb\u00e1v\u00e1n\u00ed, distribuce, metabolismu a vylu\u010dov\u00e1n\u00ed testovan\u00fdch l\u00e1tek) prok\u00e1zaly, \u017ee v d\u016fsledku p\u0159\u00edtomnosti beta-glykosidick\u00fdch vazeb nejsou glykosidy steviolu tr\u00e1veny v gastrointestin\u00e1ln\u00edm traktu, ale jsou metabolizov\u00e1ny bakteriemi ob\u00fdvaj\u00edc\u00edmi tlust\u00e9 st\u0159evo, v d\u016fsledku \u010deho\u017e se uvol\u0148uje aglykon steviolu. Tato slou\u010denina je pak vylu\u010dov\u00e1na mo\u010d\u00ed a stolic\u00ed. Na tomto z\u00e1klad\u011b bylo zji\u0161t\u011bno, \u017ee glykosidy steviolu nemaj\u00ed \u017e\u00e1dn\u00e9 kalorie. Proto se pou\u017e\u00edvaj\u00ed v potravin\u00e1\u0159stv\u00ed jakon\u00e1hra\u017eka cukru u lid\u00ed s cukrovkou nebo u lid\u00ed s inzul\u00ednovou rezistenc\u00ed<\/strong> \u2013 nezp\u016fsobuj\u00ed v\u00fdkyvy hladiny gluk\u00f3zy v krvi a uvol\u0148ov\u00e1n\u00ed inzul\u00ednu. Klinick\u00e1 data tak\u00e9 ukazuj\u00ed, \u017ee nahrazen\u00ed jednoduch\u00fdch cukr\u016f st\u00e9vi\u00ed m\u00e1 pozitivn\u00ed vliv na proces hubnut\u00ed a sn\u00ed\u017een\u00ed BMI indexu<\/strong>. <\/p>\n

<\/div>\"Glykosidy

Glykosidy steviolu 95 REB-A 80 a REB-A 60 (Stevia)<\/h2>

Glykosidy steviolu 95 REB-A 80 a REB-A 60, b\u011b\u017en\u011b zn\u00e1m\u00e9 jako st\u00e9vie nebo st\u00e9vie, jsou rostlinn\u00fdmi n\u00e1hra\u017ekami b\u00edl\u00e9ho cukru. Za svou popularitu vd\u011b\u010d\u00ed sv\u00fdm vlastnostem. Glykosidy Steviol jsou sladk\u00e9 a lze je snadno pou\u017e\u00edt jako zdravou a p\u0159irozenou n\u00e1hradu za b\u00edl\u00fd cukr.<\/p>\n<\/div>

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Kup nyn\u00ed<\/a><\/div>\n<\/div>\n\n<\/div><\/div><\/div>\n
<\/div>\n\n

St\u00e9vie<\/a> v zubn\u00ed past\u011b<\/h2>\n\n

V\u00fdzkumy tak\u00e9 ukazuj\u00ed, \u017ee glykosidy steviolu maj\u00ed pozitivn\u00ed vliv na redukci zubn\u00edho<\/strong> kazu zp\u016fsoben\u00e9ho bakteri\u00ed Streptococcus mutans<\/em>. Tento dopad m\u016f\u017ee b\u00fdt dvoj\u00ed: na jedn\u00e9 stran\u011b lid\u00e9, kte\u0159\u00ed konzumuj\u00ed potraviny obsahuj\u00edc\u00ed st\u00e9vii m\u00edsto sachar\u00f3zy, sni\u017euj\u00ed p\u0159\u00edjem cukru, kter\u00fd je nezbytn\u00fd pro r\u016fst bakteri\u00ed souvisej\u00edc\u00edch se vznikem zubn\u00edho kazu. Krom\u011b toho \u010detn\u00e9 studie ukazuj\u00ed, \u017ee extrakty st\u00e9vie mohou zpomalovat a omezovat mno\u017een\u00ed \u0161kodliv\u00fdch bakteri\u00ed a tak\u00e9 tvorbu biofilmu. Zubn\u00ed pasty s obsahem st\u00e9vie sni\u017euj\u00ed tvorbu plaku a sni\u017euj\u00ed po\u010det bakteri\u00ed spojen\u00fdch se vznikem kazu v dutin\u011b \u00fastn\u00ed. <\/strong><\/p>\n\n

V\u00fdhody konzumace st\u00e9vie<\/h2>\n\n

Mezi p\u0159\u00edzniv\u00e9 \u00fa\u010dinky st\u00e9vie pat\u0159\u00ed tak\u00e9antioxida\u010dn\u00ed, antivirov\u00e9 a imunomodula\u010dn\u00ed \u00fa\u010dinky<\/strong>. Studie prok\u00e1zaly, \u017ee glykosidy steviolu maj\u00ed protiz\u00e1n\u011btliv\u00fd \u00fa\u010dinek a zp\u016fsobuj\u00ed uvol\u0148ov\u00e1n\u00ed protiz\u00e1n\u011btliv\u00fdch cytokin\u016f. Testy vyu\u017e\u00edvaj\u00edc\u00ed lidsk\u00e9 rakovinn\u00e9 bun\u011b\u010dn\u00e9 linie rovn\u011b\u017e uk\u00e1zaly stimula\u010dn\u00ed \u00fa\u010dinek glykosid\u016f steviolu na produkci cytokin\u016f, kter\u00e9 omezuj\u00ed r\u016fst rakovinn\u00fdch bun\u011bk. <\/p>\n\n

Glykosidy steviolu a alergie<\/h2>\n\n

Jeliko\u017e metabolismus glykosid\u016f steviolu nevytv\u00e1\u0159\u00ed slo\u017eky, kter\u00e9 by mohly b\u00fdt alergenn\u00ed, m\u00e1 se za to, \u017ee jsou bezpe\u010dn\u00e9 pro alergiky a samy o sob\u011b nezp\u016fsobuj\u00ed senzibilizaci. Listy st\u00e9vie se pou\u017e\u00edvaj\u00ed ji\u017e \u0159adu let a jejich konzumace nen\u00ed spojena s v\u00fdskytem alergick\u00fdch reakc\u00ed. Hypersenzitivn\u00ed reakce na st\u00e9vii se p\u0159ed rokem 2008, p\u0159ed pou\u017eit\u00edm vysoce o\u010di\u0161t\u011bn\u00fdch glykosid\u016f steviolu, objevovaly velmi vz\u00e1cn\u011b. Od roku 2008 nebyly hl\u00e1\u0161eny \u017e\u00e1dn\u00e9 p\u0159\u00edpady p\u0159ecitliv\u011blosti na st\u00e9vii. Produkty obsahuj\u00edc\u00ed st\u00e9vii proto nemus\u00ed m\u00edt speci\u00e1ln\u00ed varovn\u00e1 ozna\u010den\u00ed pro alergiky. <\/p>\n\n

Je st\u00e9vie \u0161kodliv\u00e1?<\/h2>\n\n

V\u0161echny v\u00fd\u0161e uveden\u00e9 informace i \u010detn\u00e9 klinick\u00e9 studie jednozna\u010dn\u011b prokazuj\u00ed, \u017eeglykosidy steviolu a produkty je obsahuj\u00edc\u00ed jsou zcela bezpe\u010dn\u00e9 a zdrav\u00e9<\/strong> a mohou je konzumovat t\u011bhotn\u00e9 \u017eeny, d\u011bti a lid\u00e9 s alergi\u00ed nebo metabolick\u00fdmi chorobami.<\/p>\n\n

<\/div>\n\n
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Literatura:<\/strong><\/p>\n\n

Gardana C, Simonetti, Canzi E et al. Metabolism of Stevioside and Rebaudioside A from Stevia Rebaudiana extracts by Human Microflora, J. Ag. Food Chem, 51(2):6618-6622, 2003.<\/p>\n\n

Ferrazzano GF, Cantile T, Alcidi B, et al. Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A Review. Molecules. 2015;21(1):E38.<\/p>\n\n

European Food Safety Authority, Panel on Food Additives and Nutrient Sources added to Food. Scientific opinion on the safety of steviol glycosides for the proposed uses as a food additive. EFSA Journal, 8(4):1537. 2010. [3. Biological and toxicological data (pg 20); 3.1. Absorption, distribution, metabolism and excretion (pg 20); 3.1.1. In vitro studies (pg 20);3.1.2. In vivo studies (pg 20)]. www.efsa.europa.eu\/en\/efsajournal\/pub\/1537.htm<\/p>\n\n

European Commission Regulation (EU) No 1131\/2011 of 11 November 2011 amending Annex II to Regulation (EC) No 1333\/2008 of the European Parliament and of the Council with regard to steviol glycosides. Official Journal of the European Union. December 11, 2011. Retrieved June 13, 2013: http:\/\/eurlex.europa.eu\/LexUriServ\/LexUriServ.do?uri=OJ:L:2011:295:0205:0211:EN:PDF<\/p>\n\n

US Department of Health and Human Services and US Department of Agriculture. 2015\u20132020 Dietary Guidelines for Americans. 8th Edition. December 2015. Available at: http:\/\/health.gov\/dietaryguidelines\/2015\/guidelines\/.<\/p>\n","protected":false},"excerpt":{"rendered":"

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